منابع مشابه
Clear Path Detection
Based on the statistic of Department of Transportation, most accidents occurred by carelessness of drivers who were not aware of any obstacles ahead. Such a warning system of guiding a clear path in front can assist drivers to avoid the potential dangers and prevent accidents. In this project, a novel robust algorithm is proposed to detect clear path in real-time with the specific goal of incor...
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Our understanding of the relationship between the structure of RNA and its catalytic activity has advanced significantly in the past year. These advances include time-resolved crystallographic studies on the hammerhead ribozyme, as well as new structures of a group I intron, a lead(II)-cleavage ribozyme, a hepatitis delta virus ribozyme, and components of the spliceosome machinery and the pepti...
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Structured RNAs play an essential role in chromosome maintenance, RNA processing, protein biosynthesis, and protein transport. To understand RNA function in these diverse biological systems, the rules for RNA folding and recognition must be learned. Recent crystal structures of hammerhead ribozymes, a group I intron domain, and RNA duplexes provide new insights into the principles of RNA foldin...
متن کاملMechanisms of RNA catalysis.
Ribozymes are RNA molecules that act as chemical catalysts. In contemporary cells, most known ribozymes carry out phosphoryl transfer reactions. The nucleolytic ribozymes comprise a class of five structurally-distinct species that bring about site-specific cleavage by nucleophilic attack of the 2'-O on the adjacent 3'-P to form a cyclic 2',3'-phosphate. In general, they will also catalyse the r...
متن کاملRNA catalysis--is that it?
Ribozymes are RNA molecules that accelerate chemical reactions, enzymes that happen to be made of RNA rather than protein. Aside from the chemical challenge of trying to explain how a nucleic acid can do that, why should anyone care? Although these species created a lot of interest when the RNA journal began 20 years ago, they have slipped out of fashion more recently, and some may think RNA ca...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2015
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.1954